Improving the prediction of Alzheimer's disease using machine learning methods Lead Investigator: Victor Sheng Institution : University of Central Arkansas E-Mail : ssheng@uca.edu Proposal ID : 1040 Proposal Description: We will try to improve the prognosis of Alzheimer's disease using machine learning methods, by comparing with existing approaches. We are going to conduct research on Alzheimer?s disease classification with machine learning. Clinical evaluation data, neuropathology data, and MRI images will be used in our study. We will first conduct feature generation by using deep learning on MRI images. After that, we will perform feature selection to reduce the number of features. We will study the correlations between the features generated from images and the clinical features. Finally, we will try to improve the classification performance of Alzheimer?s disease.